Town played local football in the Salisbury League until progressing to County football in the late 50s. In the early years the club went under various guises - Amesbury, Amesbury Comrades (after WW1) and Amesbury Corinthians. The years between the wars were not a glorious time for the club, it's only success being champions of the Salisbury & District Wednesday League in 1935/36. It was not until the late 1950’s however that Town started to gain County honours, winning the Wiltshire League Division 1 title, Hospital Cup in 1959/60 and also the Wiltshire Subsidiary Cup in 1960/61.

It was some 16 seasons later that further success came to the Town, winning the Wiltshire Combination League in 1975/76 and two seasons later, lifting the Wiltshire County title for the first time in 1984.

In the late 1980’s and early 90’s the club enjoyed its most successful period, winning the Wiltshire County title twice and finishing Runners up on three occasions, as well as lifting the Wiltshire Senior Cup in 1993/94 for the second time.

It was then thought time for the Town to move forward, applying to join the Western League, duly taking it’s place in the First Division for the 1994/95 season. The first season was fairly successful, with average gates of 99 and one crowd of 200, finishing 14th place out of 21 teams.

However, the loss of key players over the next two seasons made the club struggle, finishing bottom in season 1996/97. Although Town could have continued in the Western League, the Club took the decision to pull out, mainly due to the problem of finding players willing to travel the long distances involved to fulfil fixtures and cost incurred in travelling those long distances.

It was decided to regroup and run just one senior side in the Salisbury & District League for the 1997/98 season. However the Club were looking to progress in a different direction and applied to join the Hampshire League.

The 1998/99 season, Amesbury ran their first team in the Division 3 of the Hampshire League and re introduced a Reserve side in the Salisbury League. The Club’s first season in Hampshire was fairly successful, finishing 4th. Town also had success in Wiltshire, by winning the Wiltshire Junior Cup.

The 1999/2000 season saw Amesbury meet the criteria to gain entry into the newly formed Hampshire League Premier Division, with the Reserve side in the Hampshire League Combination. The season proved to be one of the most memorable in the clubs history, winning the Premier Division title in its inaugural season, however the Reserve side had a rather disappointing season finishing in the wrong half of the Hampshire League Combination.

The 2000/01 season was not as successful as the club would have liked, failing to regain the Championship title of last season, eventually finishing in 12th position. The Youth team did however
reach the Wiltshire County FA Youth Floodlight League final, narrowly losing to Chippenham Youth.

The following seasons failed to produce a trophy but in Season 2004-5, Amesbury Town joined the Sydenhams Wessex League Division 1 after it’s merger with the Hampshire League. Its League position was disappointing but season 2006/07 proved to be a successful one in the FA Vase. Victories over Combined Counties Premier League side Cove (2-0 after 1-1 draw) and Thame United (Hellenic Premier League) 4-2 earned the club the prestigious FA Vase Team of the Round Award. Former manager Glen Butterfield returned to the club from Andover New Street to run the side.